Figure 1
From: Human-derived IgG level as an indicator for EBV-associated lymphoma model in Hu-PBL/SCID chimeras
Morphology and immunological marker examination of EBV-associated tumors in hu-PBL/SCID mice. (A) Fresh tumor tissue out of SCID mouse showed gray-white and gray-red node, size 17 × 11 × 8 mm. (B) The histopathological type of the induced-tumors was diffuse large cell lymphoma (HE × 400). (C) Positive staining of LCA located on the membrane of the tumor cells (SP × 400). (D) Immunohistochemistry revealed that positive staining of B-cell marker (CD20, L26) located on the membrane of tumor cells (SP × 400). (E) Negative staining of T-cell marker (CD45RO) of the tumor cells (SP × 400). (F) Negative staining of T-cell marker (CD3) of the tumor cells (SP × 400).