Skip to main content
Figure 4 | Virology Journal

Figure 4

From: Serine 204 phosphorylation and O-β-GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma

Figure 4

Schematic diagram illustrating the role of IGFBP-6 phosphorylation and O -glycosylation on IGF-II functions. Here we propose that alternative O-β-GlcNAc modification and phosphorylation of Ser 204 control the binding of IGF-II with IGFBP-6 during viral infection, while mid region phosphorylation and O-β-GlcNAc modifications controls it's binding with glycosaminoglycans.

Back to article page

Virology Journal

ISSN: 1743-422X