The relationship between peripheral blood lymphocyte subsets and HBV-specific CTLs. Dots indicate the mean value. CD3+CD8+ cells and HBcAg18-27-specific CTLs of AHB patients reached peak levels at the second week after admission. There was a positive correlation between them (r = 0.492, p = 0.01). The number of NK cells was negatively correlated with the frequency of the HBV specific CTLs in AHB patients (r = -0.266, p = 0.05).