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Table 4 Sites in hemagglutinin under differential selection between isolates from North American swine and the pandemic 2009

From: Positive selection on hemagglutinin and neuraminidase genes of H1N1 influenza viruses

Position1

P-value

Amino acid polymorphism2

  

North American swine

Pandemic 2009

31T

0.00512

N196

N1879/D8/X3/S1

32T

0.00222

L196

L1795/I94/X2

34BT

0.00190

E196

E1886/G2/X2/K1

39

0.00266

G196

G1887/E3/R1

48B

0.00008

A196

A1879/X6/T3/V1/P1/S1

154BT

0.00719

K195/R1

K1885/E2/X2/N1/T1

189B

0.00876

Q192/E3/L1

Q1891

197

0.00014

A192/T3/S1

A1851/T23/S17

203

0.00519

S178/T17/P1

T1341/S542/X7/A1

205B

0.00828

K166/R20/T8/Q2

R1852/K32/G2/X2/T1

207B

0.00286

N144/S43/Y5/D4

S1891

223BR

0.00199

Q196

Q1858/R18/X15

232

0.00890

T196

T1887/A1/I1/K1/X1

263B

0.00231

S196

S1889/F1/P1

304

0.00468

P196

P1875/S15/X1

306B

0.00929

Y196

Y1888/H3

374

0.00001

G183/R13

E1608/K275/G8

411T

0.00062

V196

V1839/I51/X1

427T

0.00159

V196

V1886/I5

434T

0.00550

T196

T1885/N4/X2

458T

0.00687

K196

K1885/N3/R2/E1

478T

0.00558

S196

S1889/G1/N1

479T

0.00355

V180/I16

V1891

530T

0.00409

L196

L1889/G1/X1

547T

0.00645

I195/-1

I1847/-22/K8/V5/T4/T3/C1/X1

  1. 1In this column, B indicates that the site lies in the B-cell antigenic regions [18]. T indicates that the site lies in the T-cell antigenic regions [19]. R indicates that it is a receptor-binding site [11]. We use the same numbering strategy as Deem and Pan [18] and start numbering from the amino acids DTLC.
  2. 2In these columns, capital letters stand for amino acids and numbers following them indicate the number of times they occur in the alignment. X indicates codons that are not translated properly.