Table 1 NS1 mutations in MA variant clones of A/HK/1/68 (HK-wt) H3N2.
From: Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence
Virus | NS1 Amino Acid positions | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | 2 | 23 | 98 | 103 | 106 | 124 | 125 | 180 | 226 | 227 |
HK-wt | D | V | L | F | M | M | D | V | V | R |
HKMA20 (MA20) | - | A | - | - | - | - | - | - | - | - |
HKMA20a (MA20A) | - | A | - | - | - | - | - | - | - | - |
HKMA20b (MA20B) | - | - | - | L | - | - | - | - | - | - |
HKMA20c (MA20C) | - | - | - | L | - | - | - | - | - | - |
HKMA20d (MA20d) | - | - | - | L | - | - | - | - | - | - |
HK4MA21-1 (MA41) | - | - | - | - | V | - | - | - | - | - |
HK4MA21-2 (MA42) | - | - | - | - | V | - | - | - | - | - |
HK4MA21-3 (MA43) | - | - | - | - | V | I | - | - | - | - |
HK5MA21-1 (MA51) | - | - | - | - | I | - | - | - | - | - |
HK5MA21-2 (MA52) | - | - | S | - | I | - | - | - | - | - |
HK5MA21-3 (MA53) | - | - | S | - | I | - | - | - | - | - |
HK6MA21-2 (MA62) | - | - | - | - | - | - | - | A | - | - |
HK6MA21-3 (MA63) | - | - | - | - | - | - | - | A | - | - |
HK9MA21-3 (MA93) | N | - | - | - | - | - | - | - | - | - |
HK10MA21-2 (MA102) | - | - | - | - | - | - | G | - | - | - |
HK10MA21-3 (MA103) | - | - | - | - | - | - | - | - | I | - |
HK11MA21-1 (MA111) | - | - | - | - | - | - | G | - | - | - |
HK11MA21-2 (MA112) | - | - | - | - | - | - | - | - | - | K |