Figure 6
Passive transfer of antibody from vaccinated mice protects against lethal WNV challenge. Five week-old C57BL/6 mice were pre-treated with 25 μl of serum from the indicated vaccinated mice or naïve animals at day -1 by intraperitoneal injection. On day 0, mice were infected with 102 PFU of WNV by subcutaneous route and monitored for survival. All vaccinated mice showed statistically significant protection (P < 0.05, log rank test) compared to mice receiving naïve sera. Data reflect two independent experiments with a total of n = 10 mice per arm.