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Figure 5 | Virology Journal

Figure 5

From: High Human T Cell Leukemia Virus Type-1(HTLV-1) Provirus Load in Patients with HTLV-1 Carriers Complicated with HTLV-1-unrelated disorders

Figure 5

Conceptual scheme of the fluctuations in the total proviral load (VL) in peripheral blood with no circulating abnormal cells during multi-step leukemogenesis. VL is low in the early phase of the latent period, during which infected cells consist of clones with a small population. At some time point, some clones may become large enough to be detected as bands by Southern blotting. Peak A corresponds to smears detected as polyclonal expansion by SBH, and then peaks B, C and D appear with oligoclonal bands.

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Virology Journal

ISSN: 1743-422X