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Table 1 shRNA interference of both BTBD1 and BTBD2 reduces the number of cytoplasmic bodies

From: Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection

 

S-ve*

sh-BTBD1

sh-BTBD2

sh-BTBD1 + sh-BTBD2

TOTAL cytoplasmic bodies

413

395

348

227

Total cells counted

110

104

103

105

Cytoplasmic bodies/cell

3.8

3.8

3.4

2.2

  1. * vector control
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Virology Journal

ISSN: 1743-422X