Figure 3From: A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses in vitro and in vivoPathological analysis of the lung tissues of challenged BALB/c mice. The images were obtained on an OLYMPUS BX-50 light microscope with 40× magnification. (A) Lung tissues of mice challenged with A/California/04/2009 virus; (B) Lung tissues of mice challenged with A/California/07/2009 virus; (C) Lung tissues of mice challenged with mut-A/California/04/2009 virus; (D) Lung tissues of mice challenged with mut-A/California/07/2009 virus.Back to article page