Skip to main content

Table 1 Analysis of results of tests performed for detection of HCMV with the donor-renal recipient patients

From: "pp65 antigenemia and real time polymerase chain reaction (PCR) based-study to determine the prevalence of human cytomegalovirus (HCMV) in kidney donors and recipients with follow-up studies."

Groups

Donor/Recipient

No of pairs positive by real time PCR

No of pairs positive for pp65 antigenemia

Group A

*D+/PRR-/PSR+

3/3

0/3

Sub-Group I

   

Sub-Group II

D-/PRR-/PSR+

26/26

15$/26

Sub-Group III

*D+/PRR+/PSR+

1/1

0/1

Sub-Group IV

*D+/PRR-/PSR-

2/2

0/2

Sub-Group V

D-/PRR-/PSR-

0/7

0/7

Group B

D-/PRR-/PSR+

6#/18

2/18

 

D+/PPR-/PSR+

1/18

0/18

Group C

PSR+

19^/19

19/19

 

D+

4/19

0/19

  1. In Group A,
  2. *- Donor (D), pre transplantation renal recipient (PRR) and post-transplant recipient (PSR) samples.
  3. - Post transplant recipients were tested for HCMV infections by pp65 antigenemia and viraemia by real-time PCR.
  4. - All the donors were pp65 antigenemia negative indicating that they were not infective.
  5. - * Six donors belonging to sub-groups I, III and IV were positive for HCMV by real time - PCR with copy numbers ranging from 1 to 537 copies/ml were all negative for HCMV DNA.
  6. Group B consisted of donors from whom sampling was not possible after one month
  7. of renal transplantation.
  8. Group C consisted of unrelated donors and recipients.
  9. - # Two among the recipients were positive for pp65 antigenemia also.
  10. - ^ All 19 positive for HCMV DNA were also positive for pp65 antigenemia also.
  11. - $ All 15 patients samples positive for pp65 antigenemia were also positive for real time
  12. PCR also.
  13. - Eleven more were positive only by real time PCR assay.
Back to article page

Virology Journal

ISSN: 1743-422X