Figure 3
From: Bovine herpesvirus 4 based vector as a potential oncolytic-virus for treatment of glioma
Primary cultures from two human glioblastoma analyzed 24, 48 and 72 hours post BoHV-4EGFPΔTK infection. The cells were visualized with a FITC filter for EGFP expression (a, b, c, d, e, f, bar = 50 μm) and by phase contrast (PC) (ai, bi, ci, di, ei, fi). After 72 hours post infection the cultures were completely infected. CPE induced by infection shows a prevalence of necrosis (g, h, t-test, *** p < 0.001, *p < 0.05).