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Figure 2 | Virology Journal

Figure 2

From: Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon α

Figure 2

pU19-1.24HBV was co-transfected with Renilla luciferase vector into Huh7 cells stably expressing wild-type HBc protein, L60V, S87G or I97L mutated proteins, as well as into control cells stably transfected with empty vector. MxA mRNA levels in these groups of cells were then detected by real time-PCR (a); the extracellular HBsAg level was assessed by abbot analysis (b) and the extra- and intracellular HBV DNA level (c and d respectively) was measured by real-time PCR.

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