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Table 3 HPV detection by HC-II assay and PCR Method in Clinico-pathogical parameter (OSMF grading according to Pindborg and T and N category according to UICC classification) in OSCC cases.

From: Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma

Clinico-pathogical Diagnosis

No (%) HPV detection by HC-II assay and PCR Method

 

PCR+ve,

HC-II+ve [n = 61]

PCR+ve,

HC II-ve [n = 11]

PCR-ve,

HC-II+ve [n = 09]

PCR-ve,

HC-II-ve [n = 141]

Malignant oral lesions: oral squamous cell carcinoma (OSCC), n = 222 cases

T category

    

T1-2 (80)

28 (35%)

4 (5%)

3 (3.75%)

45 (56.25%)

T3-4 (142)

33 (23.23%)

7 (4.92%)

6 (4.22%)

96 (67.6%)

N category

    

N0 (66)

21 (31.81%)

2 (3.03%)

1 (1.51%)

42 (63.63%)

N1-3 (156)

40 (2.56%)

9 (5.76%)

8 (5.12%)

99 (63.46%)