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Figure 4 | Virology Journal

Figure 4

From: Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus

Figure 4

Bio-imaging analysis of the interaction of clathrin molecules with DENV. DENV were stained green with anti-DENV E protein antibody conjugated to FITC, host clathrin stained red with anti-clathrin antibody conjugated to Texas Red (TR) and host nuclei stained blue with DAPI. (A) Attachment of DENV on the cell surface can be observed at 0 min p.i (arrow) with few co-localizations between DENV and clathrin molecules (arrows) (B) Obvious co-localization is observed between internalized DENV and clathrin by 5 minutes p.i (arrow). (C) Strong co-localization signals are observed between DENV2 and clathrin by 10 minutes p.i (arrows).

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Virology Journal

ISSN: 1743-422X