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Table 2 Baseline characteristics of cytotoxic T lymphocyte (CTL) responses in Korean subjects with primary HIV infection

From: Dynamic correlation between CTL response and viral load in primary human immunodeficiency virus-1 infected Koreans

 

Characteristics

 

Serological profile

Immunological profile

Group

At initial sampling

At follow-up*

CD4+ T cell

(cells/mm3)*

CD8+ T cell

(cells/mm3)*

Viral load

(log10 copies/mL)*

Total

(n = 50)

  

356

(129-610)

1,464

(366-5,937)

5.09

(2.53-7.84)

I

(n = 7)

EIA Ag+

EIA Ag+, EIA Ab+/-, PA+/-, WB+/-

299

(131-507)

1,322

(581-2,190)

6.08

(5.30-7.48)

II

(n = 12)

EIA Ag+

EIA Ag +/-, EIA Ab+, PA+, WB+

339

(209-614)

1,547

(520-4,955)

4.91

(3.59-6.48)

III

(n = 13)

EIA Ag+, EIA+/-, PA-, WB+/-

EIA Ag-, EIA Ab+, PA+, WB+

342

(129-765)

1,784

(366-5,937)

4.82

(3.40-6.20)

IV

(n = 18)

EIA Ab+, PA+/-, WB+/-

EIA Ag-, EIA Ab+, PA+, WB+

393

(165-610)

1,216

(446-2,432)

5.07

(2.53-6.82)

  1. * Measured at the time of HIV-1-specific CTL analysis
  2. Group I (preseroconversion group I): subjects were HIV seronegative at the initial sampling time and the follow-up duration was within 2 weeks of first referral.
  3. Group II (Preseroconversion group II): subjects were HIV seronegative at the initial sampling time and the follow-up duration was within 1 month of first referral.
  4. Group III (Seroconversion group I): subjects were starting to become seropositive at the initial sampling time and the follow-up duration was within 2 months of the first referral.
  5. Group IV (Seroconversion group II): subjects were HIV seropositive at the initial sampling time or starting to become seropositive.
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Virology Journal

ISSN: 1743-422X