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Table 1 Virus strains used in current study and previous data on ferret pathogenicity.

From: Ferrets develop fatal influenza after inhaling small particle aerosols of highly pathogenic avian influenza virus A/Vietnam/1203/2004 (H5N1)

   

Virus pathogenicity

H5N1 virus

Virus acronym

Clade

and subcladea

Original host (reference)

Ferrets (reference)

A/Vietnam/1203/2004

VN/04

1

Highb [21]

High [19–21]

A/Mongolia/244/2005

MO/05

2.2

Highc [50]

Moderate [20]

A/Iraq/207-NAMRU3/2006

IQ/06

2.2

Mildd [39]

Unknowne

  1. aBased on the phylogenetic analysis of the HA genes [34].
  2. bFatal in 10-yr-old human male.
  3. cIsolated from dead whooper swan.
  4. dMild illness in 3-yr-old human male.
  5. eNo known previously published data.