Skip to main content

Table 3 HBV Seromarker prevalence by demographic and HIV status

From: Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians

  AIDS patients Pre-treatment time-point Non-AIDS Baseline
Positive HBV Sero Markers HBsAg HBeAg 1 HBV-infected 2 HBsAg N (%) HBeAg 1 HBV-infected 2 N (%)
  N (%) N (%) N (%) N (%) N (%) N (%)
Sex:       
Male 13 (17.6) 6 (46.2) 63 (86.3) 11 (14.3) 0 (0.0) 62 (87.3)
Female 16 (13.8) 4 (25.0) 95 (77.8) 30 (9.8) 8 (26.6) 227 (83.2)
P-value difference 0.48 0.23 0.14 0.26 0.17 0.39
Age:       
10-24 years 1 (10.0) 1 (100.0) 10 (58.8)* 14 (16.9) 4 (28.6) 65 (83.3)
25-34 years 11 (19.3) 4 (36.4) 47 (92.2) * 17 (9.3) 2 (12.5) 135 (82.8)
35-44 years 13 (18.0) 4 (30.8) 59 (88.1) * 4 (6.4) 1 (25.0) 48 (82.7)
45-93 years 4 (7.8) 1 (25.0) 39 (84.8) * 6 (11.3) 1 (16.7) 42 (93.3)
P-value difference 0.31 0.54 < 0.0001 0.17 0.71 0.36
HIV status:       
HIV-1 25 (17.6) 9 (36.0) 117 (78.5) 16 (10.1) 3 (18.8) 109 (76.8)*
HIV-2 3 (10.3) 0 (0.0) 24 (85.7) 24 (11.1) 4 (17.4) 174 (89.2)*
Dual Infection 1 (5.3) 1 (100.0) 17 (99.4) 1 (11.1) 1 (100.0) 7 (87.5)*
P-value difference 0.27 0.17 0.21 0.96 0.29 0.008
CD4:       
< 200 cells μL-13 14 (13.4) 5 (31.2) 87 (84.5)*    
> 200 cells μL-1 11 (18.9) 3 (27.2) 51 (71.8)*    
P-value difference 0.35 0.82 0.04    
Total 29 (15.3) 10 (34.5) 158 (81.0) 41 (10.7) 8 (20.0) 290 (84.1)
  1. 1 HBeAg status assessed in individuals who were HBsAg positive, 2 Subjects who were HBsAg positive or HBcAb positive were considered to by HBV-infected. 164 (90%) of 183 HBsAg negative AIDS patients and 302 (89%) of 345 HBsAg negative non-AIDS individuals were tested for anti-HBc, 42 non-AIDS patients and 31 AIDS patients were HBsAg positive; 122 (74.5%) and 247 (98%) respectively had a positive anti-HBc result. 3 189 AIDS patients had CD4 measurements, 109 had values <200 cell μL-1. * Chi-Square, Fisher's exact, Rank Sum or Kruskal-Wallis p-value <0.05; all but 14 of the non-AIDS patients had CD4 counts > 200 cells μL-1 25