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Table 1 Summary of differentially expressed genes in response to infection with HPAI-H5N1 and RG modified H5N1 in A549 cell lines.

From: Host gene expression profiling in influenza A virus-infected lung epithelial (A549) cells: a comparative analysis between highly pathogenic and modified H5N1 viruses

Time-points Genes qualifying the quality criteria in replicated experiments Differentially expressed genes (+/-1.5folds, p < 0.05) Up-regulated genes Down-regulated genes
HPAI-H5N1 (A/Chicken/India/WB-NIV2664/2008)
4 h 253 40 15 25
8 h 208 24 13 11
16 h 254 101 53 48
24 h 309 111 53 58
RG Modified H5N1 (A/India/NIV/2006(H5N1)-PR8-IBCDC-RG7)
4 h 262 60 36 24
8 h 212 128 67 61
16 h 237 109 58 51
24 h 305 42 22 20