Figure 4
From: Inactivation of respiratory syncytial virus by zinc finger reactive compounds
Respiratory syncytial virus inactivation by AT-2 is accompanied by modification of the M2-1 protein. RSV was inactivated by incubation with 10 mM AT-2 for 24 hrs at 37°C (lanes 2 and 4), or with corresponding amount of DMSO (lanes 1 and 3). At the end of the incubation, RSV particles were lysed and analyzed by SDS-PAGE either in the presence (lanes 3 and 4), or in the absence (lanes 1 and 2) of β-ME, followed by immunoblotting with IgY against RSV: (A) M2-1 protein, (B) P protein, and (C) N protein.