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Table 2 Summary of the results described in Figure 2.

From: Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells

  

INS [μM]

Cells

Virus (MOI 1)

0

1

2.5

12.5

62.5

100

150

200

HeLa P4

WT

1.02 ± 0.08

1.04 ± 0.07

1.25 ± 0.09

2.16 ± 0.11

3.30 ± 0.14

5.16 ± 0.20

9.70 ± 0.43

18.93 ± 0.74

 

ΔRev

8.82 ± 0.37

9.13 ± 0.34

9.65 ± 0.41

10.98 ± 0.43

13.83 ± 0.61

16.66 ± 0.71

21.99 ± 0.94

30.16 ± 1.12

LEDGF/p75-knockdown

WT

0.04 ± 0.01

0.08 ± 0.01

0.17 ± 0.02

0.39 ± 0.03

0.69 ± 0.05

1.23 ± 0.10

3.32 ± 0.14

11.60 ± 0.57

 

ΔRev

3.93 ± 0.17

4.05 ± 0.21

4.44 ± 0.27

5.21 ± 0.38

6.92 ± 0.47

8.30 ± 0.63

10.56 ± 0.74

16.80 ± 1.01

  1. Values represent an average number of integrations per cell.