|  | INS [μM] | |||||||
---|---|---|---|---|---|---|---|---|---|
Cells | Virus (MOI 1) | 0 | 1 | 2.5 | 12.5 | 62.5 | 100 | 150 | 200 |
HeLa P4 | WT | 1.02 ± 0.08 | 1.04 ± 0.07 | 1.25 ± 0.09 | 2.16 ± 0.11 | 3.30 ± 0.14 | 5.16 ± 0.20 | 9.70 ± 0.43 | 18.93 ± 0.74 |
 | ΔRev | 8.82 ± 0.37 | 9.13 ± 0.34 | 9.65 ± 0.41 | 10.98 ± 0.43 | 13.83 ± 0.61 | 16.66 ± 0.71 | 21.99 ± 0.94 | 30.16 ± 1.12 |
LEDGF/p75-knockdown | WT | 0.04 ± 0.01 | 0.08 ± 0.01 | 0.17 ± 0.02 | 0.39 ± 0.03 | 0.69 ± 0.05 | 1.23 ± 0.10 | 3.32 ± 0.14 | 11.60 ± 0.57 |
 | ΔRev | 3.93 ± 0.17 | 4.05 ± 0.21 | 4.44 ± 0.27 | 5.21 ± 0.38 | 6.92 ± 0.47 | 8.30 ± 0.63 | 10.56 ± 0.74 | 16.80 ± 1.01 |