A systematic approach for the identification of novel, serologically reactive recombinant Varicella-Zoster Virus (VZV) antigens

Table 1 Validation of the recomLine VZV with clinically defined sera

Assay	Result	Clinically defined sera				Serologically defined VZV-IgG/IgM Neg sera^d
		Chickenpox		Zoster
		IgG	IgM	IgG	IgM	IgG	IgM
ELISA	Pos ^a	5	5	18	9	0	0
	Inc ^b	0	0	0	0	0	0
	Neg ^c	0	0	0	9	24	24
RecomLine VZV	Pos	5	5	17	11	0	0
	Inc	0	0	1	0	0	0
	Neg	0	0	0	7	24	24

NOTE. Data are no. of serum samples.
^a Pos: positive; ^bInc: inconclusive; ^cNeg: negative, ^d: as assayed by Siemens Enzygnost VZV IgG/IgM wcELISA.
RecomLine VZV strips were considered as positive when the intensity of the ORF68 band was higher than the cut-off band control.

ISSN: 1743-422X