Skip to main content
Figure 3 | Virology Journal

Figure 3

From: Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs

Figure 3

Surface representation of A/CA/04/2009 HA modeled on the known structure of 1918 HA [PDB: 1RUZ] with a sialoside bound at the active site (based on alignment to PDB: 1RVT) [11]. HA1 is shown in various shades of gray, HA2 in orange, and glycan modification of HA in brown. The bound sialoside is modeled as a ball-and-stick representation with yellow carbons and red oxygens. The positions of Ser186 (yellow) and Leu194 (red) are highlighted. The model was generated and the structure aligned with O [23], and the figure was generated with Chimera [24].

Back to article page

Virology Journal

ISSN: 1743-422X