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Table 1 Therapeutic efficacy of pegasys in 4 patients with chronic hepatitis B

From: Clinical significance of 4 patients with chronic hepatitis B achieving HBsAg clearance by treated with pegylated interferon alpha-2a for less than 1 year: a short report

Characteristics Case 1 Case 2 Case 3 Case 4
Sex Female Male Male Male
Age(yr) 14 24 39 49
Course of diseasea(yr) 3 2 1 1
Therapy Monotherapy Monotherapy Sequential therapy Sequential therapy
Course of treatmentb(wk) 36 40 24 44
HBV DNA undetectablec Week 14 Week 16 Week 20 Week 14
ALT normalization Week 36 Week 26 Week 23 Week 14
HBeAg seroconversion Week 16 Week 22 Week 23 Week 38
HBsAg clearance Week 17 Week 40 Week 24 Week 44
HBsAg seroconversion Week 20 -- -- --
  1. yr, year; wk, week; ALT, alanine aminotransferase; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus.
  2. a interval between the first time when HBsAg-positive was detected and the date before treatment.
  3. b cumulate course between the first day of anti-HBV treatment and the date when complete response occurred.
  4. c HBV DNA<1000 copies/ml.