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Table 3 Clinical and laboratory history of genital HPV infection during pregnancy and delivery and distribution of HPV types in maternal, newborns and children in 1st and 6th and 12th month of life samples.

From: Perinatal transmission of human papilomavirus DNA

 

Maternal epidemiology

HPV type in samples

 

Pregnancy

Delivery

Maternal

Newborn

Children

         

Buccal

Case

HPV lesion type

HPV lesion site

Type

HPV lesion

Genital

Nasopharyngeal aspirates

Buccal and body

Cord blood

1st month of life

6th month of life

12th month of life

1

Warts

VV

V

No

6/11

      

2

HGSIL

C

C

No

16+6/11

 

6/11

 

6/11

  

3

HGSIL

C

C

Yes

16+31

      

4

Warts

VV

V

No

16+42+54

 

42

    

5

LGSIL

C

C

Yes

18

      

6

Warts

VV

C

No

6/11+16+31

      

7

Warts

C+VV+VG

V

No

6/11+42

6/11

6/11

    

8

HGSIL

C

C

Yes

52

6/11

     

9

LGSIL

C

V

Yes

42+51+NC*

      

10

Warts

VV+VG

V

No

6/11

      

11

LGSIL

C

V

No

18

18

 

18

   

12

Warts

VV

V+F

No

NC*

      

13

LGSIL

C

C

Yes

6/11+42

      

14

LGSIL

C

C

Yes

16+42+58

59

     

15

Warts

C+VV+VG

V

Yes

6/11+42

      

16

Warts

VV+VG

C

No

6/11

    

6/11

 

17

HGSIL

C

C

Yes

18+51

      

18

Warts

VV+P

C

No

42+59

      

19

Warts

VV

V

No

6/11

      

20

HGSIL

C

C

No

42+35

      

21

Warts

VV

C

Yes

52

  

52

   

22

Warts

VV

C

Yes

34

      

23

Warts

VV+VG

V

Yes

18

      

24

Warts

VV

V

No

16+73

      

25

Warts

VV+VG

C

No

68

      

26

Warts

C

V

Yes

6/11+16

   

16

  

27

Warts

C+VV+VG

V

No

16+58

      

28

Warts

VV

C

Yes

6/11+33

      

29

LGSIL

C

V

No

16

      

30

LGSIL

C

V

Yes

52+42+58+54

      

31

LGSIL

C

C

No

16

      

32

Warts

VV

C

No

6/11

      

33

HGSIL

C

V

Yes

18

      

34

Warts

VV

V

Yes

11

11

     

35

Warts

VV+VG

C

Yes

42

 

42

    

36

LGSIL

C

V

Yes

16

      

37

HGSIL

C

C

Yes

58

 

6/11+52

 

6/11

  

38

HGSIL

C

V

No

6/11+18

   

6/11

  

39

HGSIL

C

C

Yes

18+31

      

40

Warts

VV

V

No

6/11

      

41

Warts

VV

C

No

42+35+NC*

      

42

LGSIL

C

C

Yes

42

      

43

LGSIL

C

C

Yes

16+18+42

      

44

LGSIL

C+VV+VG

C

Yes

18+26

      

45

Warts

VV

V

Yes

6/11+58+59

 

6/11

6/11

   

46

Warts

VV+VG

C

Yes

6

      

47

Warts

VV

V

Yes

35

      

48

Warts

VV

V

No

70

      

49

Warts

VV+VG

V

No

6+45

   

6/11+52

  

50

LGSIL

C

V

Yes

-

      

51

Warts

VV

C

No

-

      

52

HGSIL**

C

C

Yes

-

      

53

Warts

VV+VG

C

Yes

-

      

54

HGSIL

C

V

Yes

-

      

55

LGSIL

C

V

Yes

-

      

56

HGSIL

C

V

Yes

-

      

57

HGSIL

C

V

No

-

      

58

HGSIL

C

C

No

-

      

59

HGSIL

C

C

Yes

-

      

60

LGSIL

C

V

No

-

      

61

HGSIL

C

V

Yes

-

      

62

LGSIL

C

C

Yes

-

      

63

HGSIL

C

V

Yes

-

      
  1. The HPV types were identified by both multiplex PCR and nested multiplex PCR methods.*NC = HPV-DNA positive but could not be classified by type. **Child had anogenital warts (HPV type 6/11) in the 12th month of life.
  2. Delivery type = C – cesarean section; V- vaginal; and V+ F – vaginal with forceps.
  3. HPV lesion site = C – cervical; VG – vaginal; VV – vulva; P- perineal.
  4. HPV lesion type = Warts – genital warts; LGSIL – low-grade squamous intraepithelial lesions; HGSIL – high-grade squamous intraepithelial lesions.
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Virology Journal

ISSN: 1743-422X