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Table 1 Reduction of HSV-1 DNA levels upon treatment with ODNs in Vero and MRC-5 cells.

From: Short hairpin-loop-structured oligodeoxynucleotides reduce HSV-1 replication

Treatment

Average fold reduction of the mean (median)

 

Co-application

Transfection with subsequent infection

 

Vero

Vero

MRC-5

PBS

1.0 (1.0)

1.0 (1.0)

1.0 (1.0)

Control

1.4 (1.4)

1.0 (1.0)

1.1 (1.1)

ODN 5

3.3 (6.5)

3.0 (5.0)

2.5 (2.2)

ODN 29

3.9 (4.1)

1.8 (1.3)

1.6 (2.4)

ODN 30

4.1 (4.1)

0.7 (1.3)

1.5 (1.6)

ODN 48

2.2 (3.1)

1.4 (1.7)

n. d.

ODN48G

2.9 (3.6)

2.4 (2.4)

1.9 (2.0)

  1. The data of all in vitro experiments are summarized. The average fold reductions of the mean and the median are shown (n. d., not determined).
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Virology Journal

ISSN: 1743-422X