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Figure 3 | Virology Journal

Figure 3

From: Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization

Figure 3

L1 binding and neutralizing antibodies in sera of mice immunized with pL1op and psL1op. (A) Mice (n = 5) received empty vector, pL1op or psL1op by gene gun on day 0 and after 3 and 6 weeks. Mice were bled at 3, 6 and 8 weeks after the first immunization. Antibody binding to L1 was determined by ELISA. Arrows point to days of immunization. (B) Neutralizing antibodies (IC50) were measured at 8 weeks using a flow cytometry assay.

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Virology Journal

ISSN: 1743-422X