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Figure 4 | Virology Journal

Figure 4

From: Retinoic acid inducible gene I Activates innate antiviral response against human parainfluenza virus type 3

Figure 4

Silencing of endogenous RIGI in A549 cells results in loss of induction of antiviral response. (a) RT-PCR analysis of RIGI expression in mock and HPIV3 infected (at 12 h post-infection) A549 cells transfected with either control siRNA or RIGI specific siRNA. (b) RT-PCR analysis of TNF expression in mock and HPIV3 infected (at 12 h post-infection) A549 cells transfected with either control siRNA or RIGI specific siRNA. (c) RT-PCR analysis of IFN-β expression in mock and HPIV3 infected (at 12 h post-infection) A549 cells transfected with either control siRNA (Con siRNA) or RIGI specific siRNA (RIGI siRNA).

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