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Figure 5 | Virology Journal

Figure 5

From: Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions

Figure 5

Nedd4 and UL56 colocalized to trans-Golgi network in HSV-2 infected cells. Cells were transfected with a Nedd4-GFP expressing plasmid, subsequently infected with wild-type HSV-2, fixed at indicated times postinfection, immunostained for UL56 and either TGN46 (A) or CD63 (B). (A) Nedd4-GFP (shown in green) and UL56 (shown in red) substantially colocalizes to TGN46 (shown in blue). (B) Nedd4-GFP and UL56 shows no (at 6 or 12 h postinfection [hpi]) or little (at 9 h postinfection) colocalization with CD63 (shown in blue). Scale bars, 10 μm.

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Virology Journal

ISSN: 1743-422X