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Figure 2 | Virology Journal

Figure 2

From: Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation

Figure 2

An overview of the pRHGP12-RSN Gene Search Vector (GSV). Unique and important features of the vector are highlighted that facilitate the RHGP-based identification of host-based gene targets contributing to HIV-1 resistance. Note that the promoter used for production of the GSV "Packaging Promoter" is not included into the GSV viral genome and the 5' LTR is replaced with the SIN 3'LTR after the vector integrates into the cellular genome.

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