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Table 2 Nucleotide and amino acid substitutions in the informative sites of genotype II.

From: Genetic diversity of the E Protein of Dengue Type 3 Virus

Nucleotide

Protein

Domains

  

Genotype II

     
    

Lineage I

Lineage II

Position

Lineage I

  

Position

Lineage

Sub-Lineage

Sub-Lineage

 

Sub-Lineage

Type of amino acid Changes

 

Gene

Codon

I

II

I

II

I

II

Protein

I

II

  

54

3

  

T

A

      

I

90

3

    

C

T

     

96

3

    

T

C

     

273

3

  

A

G

      

II

351

3

  

G

A

       

419

2

  

T

C

  

140

I

T

Nonconservative

I

549

3

  

C

T

       

525

3

A

G

         

558

3

  

G

C

       

609

3

A

C

        

II

708

3

G

A

         

747

3

  

T

C

       

834

3

  

T

C

       

963

3

  

G

A

      

III

1002

3

T

C

         

1134

3

  

G

C

       

1176

3

  

T

A

       

1188

3

  

C

C

      

TM

1233

3

  

A

T

       

1339

1

  

T

G

  

447

S

G

Nonconservative

 

1436

2

  

G

C

       

1465

1

  

A

A

       

1467

3

  

T

T

  

489

A

T

Nonconservative

 
  1. Domain I: 1–156nt (1–52aa); 397–573nt (133–191aa); 835–882nt (279–294aa)
  2. Domain II: 157–396nt (53–132aa); 574–834nt (192–278aa)
  3. Domain III: 883–1176nt (295–392aa)
  4. Domain TM: 1177–1479nt (393–493aa)
  5. nt:are indicated the nucleotide positions
  6. aa::are indicated the amino acid positions