Figure 1

DENV-3 phylogenetic tree based on the E gene sequences. The three was constructed using the method of Neighbor-joining with 1000 bootstrap replications. The genotypes are labeled according to the scheme of Lanciotti (1994) and the amino acid changes distinguishing each genotype are shown on the tree. Protein E gene sequences of DENV-1, DENV-2 and DENV-4 were used as outgroup. Branch lengths are proportional to percentage of divergence. Tamura Nei (TrN+I+G) nucleotide substitution model was used with a proportion of invariable sites (I) of 0.3305 and gamma distribution (G) of 0.9911. Bootstrap support values are shown for key nodes only.