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Figure 6 | Virology Journal

Figure 6

From: Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum

Figure 6

Ability of synthetic 3-hydroxy lauric acid to inhibit HIV infectivity. Increasing concentrations of 3-hydroxy lauric acid were incubated with HIV and added to HeLa37 cells. At 40 h following infection, cells were fixed and evaluated for HIV antigen staining. The cellular cytotoxicity of 3-hydroxy lauric acid was evaluated in parallel, in the absence of HIV. The findings are shown as percent control values (the cytotoxicity or number of HIV antigen-positive cells in the presence of the various concentrations of 3-hydroxy lauric acid divided by the cytotoxicity or number of HIV antigen-positive cells in the absence of the compound). Studies were performed three times in triplicate and shown are means and standard error of the means. *p = 0.05. **p = 0.005; ***p = 0.0001.

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