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Table 7 The polymorphisms in Helical Domain III of Vpr (residues 54–77)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue Residues in NL4-3 Vpr Variant residue(s) noted in viruses of different clades Number of variants
55 A E, G, I, L, M, P, Q, R, S, T, V 11
56 G E, R 2
57 V A, L, M, W 4
58 E A, G, I, K, L, M, Q, R, T, V 10
59 A D, F, I, L, M, N, P, S, T, V 10
60 I F, L, M, T, V, Y 6
61 I A, L, M, T, V, Y 6
62 R I, K, L, Q, S, T, W 7
63 I F, L, M, S, T, V, Y 7
64 L F, V 2
65 Q H, R 2
66 Q H, K, L, R 4
67 L A, F, I, M, P, Q 6
68 L I, M, P, R 4
69 F L, S, V 3
70 I A, T, V 3
71 H L, Y 2
72 F S, Y, L 3
73 R G, S, T 3
74 I F, H, L, M, N, S, T, V 8
75 G K, R 2
76 C G, S, Y 3
77 R A, H, L, K, N, P, Q, S, T, W 10