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Table 3 The polymorphisms in Helical Domain I of Vpr (residues 17–33)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue Residues in NL4-3 Vpr Variant residue(s) noted in viruses of different clades Number of variants
17 E A, D, G, Q, T, V 6
18 W G, R 2
19 T A, I, L, M, P, R, S, V 8
20 L I, M, V 3
21 E A, D, G, K, T 5
22 L F, I, M, P, T, V 6
23 L S, V 2
24 E D, G, K, Q, R 5
25 E A, D, G, K 4
26 L F, I 2
27 K I, M, N, Q, R 5
28 S A, D, E, G, H, I, K, N, Q, R, T, V 12
29 E D, G, Q, V 4
30 A D, P, S, T, V 5
31 V A, D, I, L, M, T 6
32 R G, K, Q, T, W, 5
33 H R 1