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Table 3 The polymorphisms in Helical Domain I of Vpr (residues 17–33)

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Residue

Residues in NL4-3 Vpr

Variant residue(s) noted in viruses of different clades

Number of variants

17

E

A, D, G, Q, T, V

6

18

W

G, R

2

19

T

A, I, L, M, P, R, S, V

8

20

L

I, M, V

3

21

E

A, D, G, K, T

5

22

L

F, I, M, P, T, V

6

23

L

S, V

2

24

E

D, G, K, Q, R

5

25

E

A, D, G, K

4

26

L

F, I

2

27

K

I, M, N, Q, R

5

28

S

A, D, E, G, H, I, K, N, Q, R, T, V

12

29

E

D, G, Q, V

4

30

A

D, P, S, T, V

5

31

V

A, D, I, L, M, T

6

32

R

G, K, Q, T, W,

5

33

H

R

1