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Table 19 Effect of variant amino acids on CTL Epitope corresponding to residues 38–46 of Vpr

From: A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

Amino Acid Sequence of Predicted Epitope Scoreβ
Prototype sequence (start position 38)α  
WLHELGQQI 196.763
Natural variations observed at this epitope  
CLHELGQQI 42.774
FLHELGQQI 196.763
TLHELGQQI 42.774
YLHELGQQI 196.763
WFHELGQQI 0.137
WLIELGQQI 196.763
WLLELGQQI 728.022
WLMELGQQI 728.022
WLNELGQQI 196.763
WLQELGQQI 196.763
WLRELGQQI 14.954
WLTELGQQI 196.763
WLYELGQQI 629.64
WLHALGQQI 47.991
WLHDLGQQI 196.763
WLHGLGQQI 47.991
WLHHLGQQI 47.991
WLHNLGQQI 47.991
WLHQLGQQI 47.991
WLHRLGQQI 47.991
WLHSLGQQI 47.991
WLHWLGQQI 47.991
WLHECGQQI 196.763
WLHEFGQQI 747.698
WLHEIGQQI 196.763
WLHEMGQQI 196.763
WLHEVGQQI 196.763
WLHELGEQI 96.414
WLHELGHQI 196.763
WLHELGKQI 196.763
WLHELGLQI 196.763
WLHELGNQI 196.763
WLHELGRQI 39.353
WLHELGTQI 196.763
WLHELGVQI 196.763
WLHELGQFI 1082.194
WLHELGQHI 196.763
WLHELGQLI 196.763
WLHELGQWI 1082.194
WLHELGQYI 1082.194
WLHELGQQD 0.281
WLHELGQQV 1311.751
  1. α Accession No.: A1.TZ.01.A341_AY253314
  2. β Estimate of Half Time of Disassociation of a Molecule Containing This Epitope