Complete genome of a European hepatitis C virus subtype 1g isolate: phylogenetic and genetic analyses

Table 1 Mean genetic distances among HCV subtype 1 representative sequences

	subtype 1a	subtype 1b	subtype 1c	Unassigned subtype 1	subtype 1g
subtype 1a (n = 10)		0.021	0.019	0.013	0.018
subtype 1b (n = 12)	0.690		0.019	0.014	0.012
subtype 1c (n = 2)	0.563	0.715		0.006	0.022
Unassigned subtype 1 (n = 1)	0.627	0.480	0.656		NA
subtype 1g (n = 1)	0.709	0.726	0.729	0.711

NA, not applicable.
Mean genetic distances (lower-left matrix) among the HCV subtype 1g and representative sequences from subtypes 1a, 1b, 1c and an unassigned subtype 1 sequence. A codon-based nucleotide alignment containing the polyprotein of 26 complete genomes (9066 nucleotides) was used for distance estimates. Standard deviations are indicated in the upper-right matrix. Distance model was GTR+I+G with assumed proportion of invariable sites of 0.42 and a shape parameter (alpha) of 1.02 for the gamma distribution of substitution rates at variable sites. The number of sequences included in each subtype group is indicated in parenthesis.

ISSN: 1743-422X