|
HPV Type (E6)
|
PDZ domain
|
|---|
|
18
|
L
|
Q
|
R
|
R
|
R
|
E
|
T
|
Q
|
V
|
|
45
|
L
|
R
|
R
|
R
|
R
|
E
|
T
|
Q
|
V
|
|
70
|
R
|
R
|
I
|
R
|
R
|
E
|
T
|
Q
|
V
|
|
58
|
R
|
P
|
R
|
R
|
R
|
Q
|
T
|
Q
|
V
|
|
16
|
S
|
R
|
T
|
R
|
R
|
E
|
T
|
Q
|
L
|
|
35
|
K
|
P
|
T
|
R
|
R
|
E
|
T
|
E
|
V
|
|
51
|
T
|
R
|
Q
|
R
|
N
|
E
|
T
|
Q
|
V
|
|
82
|
A
|
R
|
Q
|
R
|
S
|
E
|
T
|
Q
|
V
|
|
33
|
R
|
S
|
R
|
R
|
R
|
E
|
T
|
A
|
L
|
|
56
|
S
|
R
|
E
|
P
|
R
|
E
|
S
|
T
|
V
|
|
66
|
S
|
R
|
Q
|
A
|
T
|
E
|
S
|
T
|
V
|
|
53
|
H
|
T
|
T
|
A
|
T
|
E
|
S
|
A
|
V
|
- Comparison of the C-terminal PDZ-binding domains for E6 from high-risk HPV types relative to HPV-18 E6. Amino acid sequences homologous to HPV-18 are highlighted in boldy and amino acids matching the consensus PDZ-binding sequence X-T/S-X-V/L are underlined.
