Table 3 Mortality of BALB/c Mice Inoculated Intranasally with Wild Type or CDV Resistant Vaccinia Viruses
From: Isolation and characterization of cidofovir resistant vaccinia viruses
Mortality | ||||
|---|---|---|---|---|
Virusa | Number | Percent | MDDb | LD90 |
VV-WR, UAB c | ||||
2.8 × 104 | 10/10 | 100 | 7.1 | 2.9 × 103 |
2.8 × 103 | 7/10 | 70 | 8.1 | -- |
2.8 × 102 | 2/10 | 20 | 9.0 | -- |
28 | 0/10 | 0 | -- | -- |
2.8 | 0/10 | 0 | -- | -- |
VV-WR, Moyer c | ||||
1.3 × 104 | 10/10 | 100 | 7.8 | <1.3 × 104 |
1.3 × 103 | 0/10 | 0 | -- | -- |
1.3 × 102 | 0/10 | 0 | -- | -- |
13 | 0/10 | 0 | -- | -- |
1.3 | 0/10 | 0 | -- | -- |
CDV R 1A c | ||||
Stock 1.2 × 104 | 0/10 | 0 | -- | >1.2 × 104 |
1.2 × 103 | 0/10 | 0 | -- | -- |
1.2 × 102 | 0/10 | 0 | -- | -- |
12 | 0/10 | 0 | -- | -- |
1.2 | 0/10 | 0 | -- | -- |