|
Virus
|
Gene
|
Protein
|
human chemokine receptor targets
|
Ref
|
also targeting the corresponding murine chemokine receptor
|
Ref
|
|---|
|
CMV
|
UL146
|
vCXCL1
|
Selective CXCR2 agonist
|
11
|
No
|
20
|
| |
UL147
|
vCXCL2
|
?
| | | |
|
HHV6
a
|
U83B
|
vCCL4
|
Selective CCR2 agonist
|
9
|
?
| |
|
HHV8
|
K6
|
vCCL1 (vMIP-I)
|
Selective CCR8 agonist
|
3,5,10
|
Yes
|
18
|
| |
K4
|
vCCL2 (vMIP-II)
|
Broadspectrum chemokine receptor
| | | |
| | | |
antagonist
| | | |
| | | |
CCR1
|
6,7
|
Yes
|
19
|
| | | |
CCR2
|
6,7
|
Yes
|
19
|
| | | |
CCR5
|
6,7
|
Yes
|
19
|
| | | |
XCR1
|
7
|
No
|
This paper
|
| | | |
CX3CR1
|
7
|
?
| |
| | | |
CXCR4
|
6,7
|
?
| |
| | | |
CCR3 agonist
|
17
|
?
| |
| |
K4.1
|
vCCL3 (vMIP-III)
|
Selective XCR1 agonist
|
10
|
No
|
This paper
|
|
MCV
|
MC148
|
MCC
|
Selective CCR8 antagonist
|
7
|
No
|
18
|
- aThe protein product from the U83 gene of HHV6A has not been included as its signal sequence include a premature stop codon.
