Archived Comments for:
Therapeutic immunisation of rabbits with cottontail rabbit papillomavirus (CRPV) virus-like particles (VLP) induces regression of established papillomas
Vaccination group different before vaccines started
Farrel Buchinsky, Allegheny-Singer Research Institute
7 May 2009
The papilloma sizes in the two groups (control vs. cotton tail rabbit papillomavirus virus-like particles) clearly had a very different course as depicted in Figure 1. Why was there a difference between the groups one week before vaccination (week 7) and a more stark difference at the time of commencing the vaccine (week 8). Does the difference increase the chance of the overall result being a false positive?
How does this rabbit paper relate to a similar study that was done in dogs? Kuntsi-Vaattovaara H et al. Resolution of persistent oral...[PMID: 19379331]pubmed link
Virology Journal
Vaccination group different before vaccines started
7 May 2009
The papilloma sizes in the two groups (control vs. cotton tail rabbit papillomavirus virus-like particles) clearly had a very different course as depicted in Figure 1. Why was there a difference between the groups one week before vaccination (week 7) and a more stark difference at the time of commencing the vaccine (week 8). Does the difference increase the chance of the overall result being a false positive?
How does this rabbit paper relate to a similar study that was done in dogs? Kuntsi-Vaattovaara H et al. Resolution of persistent oral...[PMID: 19379331]pubmed link
Competing interests
None declared