The first hydrophobic region of the HPV16 E5 protein determines protein cellular location and facilitates anchorage-independent growth

Table 1 Colocalisation in HaCaT cells of E5 proteins with markers specific for ER, trans-Golgi network, early endosomes, or lysosomes.

		Colocalisation with
	Calnexin (endoplasmic reticulum)	58 k (trans-Golgi network)	EEA1 (early endosomes)	Lamp-1 (lysosomes)
Construct
hE5	++	-	+++	+
hE5H75	+/-	-	+/-	+
hE5R58	+	-	++	+
hE5R30	++	-	++	+
R30hE5	-	-	- (dubious +/-)	-

Relative intensity of colocalisation is shown by symbols: -, no colocalisation; -/+, occasional colocalisation; +, weak colocalisation; +++, strong colocalisation.

ISSN: 1743-422X