Figure 4

Alignment of the class I penetrenes of orthomyxoviruses. Alignment of HE2 of influenza C virus with HA2 of influenza A and B virus and F₁ of ISAV. Fusion peptide red, amino terminal helix (N-helix) orange, c-terminal helix (green), aromatic domain (indigo). Hydrophobic transmembrane domains (violet).