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Table 1 The positions of sites identified as under positive selection across multiple HIV-1M lineages.

From: Conserved positive selection signals in gp41 across multiple subtypes and difference in selection signals detectable in gp41 sequences sampled during acute and chronic HIV-1 subtype C infection

Codon position (HXB2 gp41)

Selection analysis method

Detected elsewherea

 

SLAC

FEL

IFEL

 

24

 

B, D

B, D

T, C

54

 

B, F, CRF 02_AG

CRF 01_AE

 

96

C, D

C, A, D

C, B, D, CRF 01_AE

T

101

B, G

B, G

B, G

 

130

B

C, A, B

C, B

T

137

A, B

A, B, G

B

T

163

C, D, CRF 02_AG

C

C, D, CRF 02_AG

C

165

D, G

 

C, A, G

 

172

 

C, B, G, CRF 02 _AG

  

210

C, A, CRF 01_AE

C, A, B, D, F, G

C, D, CRF 01_AE

 

214b

A

A, B

A, B

 

221

G, CRF 01_AE

C, A, G, CRF 01_AE, CRF 02_AG

C, D, G, CRF 01_AE

 

230

 

A, D

A, G, CRF 01_AE

 

271

 

C, CRF 01_AE

C, B, D

 

328

C, B, G

C, B, G

C, B, G

 

332

A, B, G

A, B, G

B, D, G, CRF 01_AE

C

349

 

C, F, CRF 01_AE, CRF 02_AG

CRF 02_AG

C

  1. aT = Travers et al (2005), C = Choisy et al (2003).
  2. bHighlighted in yellow are sites that fall within the overlapping reading frame of the rev exon 2.