Figure 4
From: Ex vivo promoter analysis of antiviral heat shock cognate 70B gene in Anopheles gambiae
hsc70B promoter activity (mean ± SD) time course experiments during ONNV infection. (A) The hsc70B promoter activity, as measured by luciferase activity, was significantly higher at 48 h (P < 0.01, t = 8.53, df = 4) and 72 hpi (P < 0.01, t = 27.34, df = 4) in the ONNV infected samples. ONNV titers were also markedly elevated at 48 and 72 hpi. The induction of the HSC70B promoter corresponds to viral titer. (B) ONNV cytopathic effects in Vero cells; CPE are clearly evident at 48 and 72 hpi.