Figure 4
From: Characterization of vaccinia virus A12L protein proteolysis and its participation in virus assembly
The predicted molecular weights and pI's of potential A12L cleavage products. The schematic cleavage products at each AG/X site were drawn with the molecular weights of 6, 6.5, 3.6, and 4.4 kDa. Utilizing single and double AG/X sites, proteolytic processing of A12L were predicted as follows: cleavage at the middle AG/K site would only produce a 12 kDa and a 8 kDa peptide, while cleavages at the C-terminus AG/K site and the N-terminus AG/A site only would introduce a 16 kDa and a 15 kDa product (bottom), respectively. The utilization of both AG/A and N-terminal AG/K site would generate a 10 kDa peptide.