Figure 3

Potential RNA secondary structure of the complex formed by NL4-EcoLys3 viral RNA and E. coli tRNALys,3. The tRNA:RNA structure was adapted from that described in previous studies [5,6]. The mutations at nucleotides 54 and 53 of E. coli tRNALys1,2 are boxed. The T54G mutation would be predicted to destabilize the interaction (G:G), while the TG5453CC mutation should stabilize by favorable G:C interaction.