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Table 4 Development of C.B-17 SCID mouse fetusesa.

From: Transplacental murine cytomegalovirus infection in the brain of SCID mice

USGS Litters
Embryonic Stage Number Litters Number Fetusesb Number Remnantsc Body Weight (Mean ± SE) Crown-Rump Length (Mean ± SE)
E12 4 32 3 0.07 g ± 0.01 8.51 mm ± 0.23
E14 5 32 5 0.20 g ± 0.01 11.04 mm ± 0.11
E16 6 19 8 0.78 g ± 0.06 17.25 mm ± 0.77
E18 18 75 15 1.00 g ± 0.03 19.08 mm ± 0.28
MCMV Litters
Embryonic Stage Number Litters Number Fetuses b Number Remnants c Body Weight (Mean ± SE) Crown-Rump Length (Mean ± SE)
E12 5 29 (11)d 7 0.07 g ± 0.01 (0.05 g ± 0.01)d 8.14 mm ± 0.24 (6.65 mm ± 0.41)d*
E14 5 24 (12) 10 0.18 g ± 0.01* (0.17 g ± 0.02)* 10.61 mm ± 0.20 (10.46 mm ± 0.37)
E16 6 32 (8) 9 0.51 g ± 0.02** (0.52 g ± 0.03)* 14.42 mm ± 0.23** (14.06 mm ± 0.38)*
E18 16 94 (50) 16 0.82 g ± 0.02** (0.81 g ± 0.02)* 18.05 mm ± 0.19** (18.18 mm ± 0.28)**
  1. a: SCID mouse dams were intraperitoneally injected with either USGS or 103 PFU of MCMV at E4, and live fetuses were collected at the indicated embryonic (E) stages.
  2. b: Live fetuses pooled across litters.
  3. c: Dead/reabsorbed fetuses pooled across litters.
  4. d: (fetuses nPCR MCMV DNA positive in brains and/or viscera).
  5. Statistical significance levels (USGS vs. MCMV): * p < 0.05, ** p < 0.01, Student's t-tests.