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Table 4 Development of C.B-17 SCID mouse fetusesa.

From: Transplacental murine cytomegalovirus infection in the brain of SCID mice

USGS Litters

Embryonic Stage

Number Litters

Number Fetusesb

Number Remnantsc

Body Weight

(Mean ± SE)

Crown-Rump Length

(Mean ± SE)

E12

4

32

3

0.07 g ± 0.01

8.51 mm ± 0.23

E14

5

32

5

0.20 g ± 0.01

11.04 mm ± 0.11

E16

6

19

8

0.78 g ± 0.06

17.25 mm ± 0.77

E18

18

75

15

1.00 g ± 0.03

19.08 mm ± 0.28

MCMV Litters

Embryonic Stage

Number Litters

Number Fetuses b

Number Remnants c

Body Weight

(Mean ± SE)

Crown-Rump Length

(Mean ± SE)

E12

5

29 (11)d

7

0.07 g ± 0.01

(0.05 g ± 0.01)d

8.14 mm ± 0.24

(6.65 mm ± 0.41)d*

E14

5

24 (12)

10

0.18 g ± 0.01*

(0.17 g ± 0.02)*

10.61 mm ± 0.20

(10.46 mm ± 0.37)

E16

6

32 (8)

9

0.51 g ± 0.02**

(0.52 g ± 0.03)*

14.42 mm ± 0.23**

(14.06 mm ± 0.38)*

E18

16

94 (50)

16

0.82 g ± 0.02**

(0.81 g ± 0.02)*

18.05 mm ± 0.19**

(18.18 mm ± 0.28)**

  1. a: SCID mouse dams were intraperitoneally injected with either USGS or 103 PFU of MCMV at E4, and live fetuses were collected at the indicated embryonic (E) stages.
  2. b: Live fetuses pooled across litters.
  3. c: Dead/reabsorbed fetuses pooled across litters.
  4. d: (fetuses nPCR MCMV DNA positive in brains and/or viscera).
  5. Statistical significance levels (USGS vs. MCMV): * p < 0.05, ** p < 0.01, Student's t-tests.