Figure 5
From: Pathogeneses of respiratory infections with virulent and attenuated vaccinia viruses
Characterization of T lymphocytes in the lung at 5 days post-infection. Mice were intranasally infected with 106 p.f.u. or 104 p.f.u. of WR or 106 p.f.u. of Wyeth strain. Cells were isolated from lungs and stained for T cell specific markers CD3, CD4 and CD8. (A) The percentage of lymphocytes in total lung cells isolated from uninfected control and infected mice. (B) Histograms of CD3 expression in lymphocytes from the lung. The percentages of CD3 intermediate (int) and CD3 high (high) subsets are shown in each histogram. (C) CD4 and CD8 expressions in CD3int and CD3high subsets. Data are representative of the lymphocyte subsets obtained from uninfected mice lungs. (D) CD4 and CD8 expressions in CD3 positive cells (CD3int and CD3high) from uninfected control and infected mice lungs. The percentages of CD4 high and CD4 intermediate are shown in each diagram.