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Figure 3 | Virology Journal

Figure 3

From: Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages

Figure 3

Replication of HIV-1 subtype C env V3–V5 region chimeras in primary peripheral blood T-lymphocytes (PBL). PBL (1 × 106 cells/well) were stimulated with PHA and infected with equal amounts (reverse transcriptase counts) of subtype C env V3–V5 region chimeras, subtype B env V3 region chimeras, primary subtype B isolates, primary subtype C isolates and parental HIV-1NL4-3. Cells were fed every 3 days with appropriate medium and virus production was measured in the culture supernatant by RT assay. The data are presented as cpm/ml ± SD on triplicate experiments and are based on PBL from five different donors.

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Virology Journal

ISSN: 1743-422X