Sequence and predicted secondary structures of the LLP domains. (A) Wimley-White hydrophobicity plot of TM predicted amino acid sequence of HIVHXB2. Highlighted cylinders show the locations of the LLP domains. A hydrophibicity score could not be calculated for the entire LLP-1 domain due to its location at the extreme c-terminus of TM. (B) Helical wheel diagrams showing the amphipathic nature of each LLP domain. The coloring scheme is from Benner et al. and graphs were generated using a java applet . (C) Primary amino acid sequence of the synthesized peptides used in subsequent experiments which correspond to the LLP-1, -2, and -3 domains of the TM protein.